Statistically, citral activity on LNCaP prostate cancer is equal to that of C. citratus and corespond third of that presented by cisplatin, a reference used in cancer chemotherapy. The highest numbers of species were from Families Lamiaceae (13) and Asteraceae (11). e increased reliance, indicate that there is an urgent need for the preservation and, extensive investigation of these products to, clinical eectiveness. Rev., 58:621–681. They grow to be up to 60 ft tall and provide wonderful shade because of the tree’s dense foliage. A list of plants commonly cited for their medicinal uses in Ghana has also been given. These diseases are concentrated in rural areas, conflict zones and urban slums in Africa and other tropical areas. Useful plants of Ghana, West Africa. Ethnopharmacological Studies of Plants with Anagelsic Properties. Policies and protocols outlining the definition, process and goals of integration were lacking, with respondents sharing different views about the purpose and value of integration of herbal medicine within public health facilities. It is expected that the fruit juice of Morinda citrifolia will cause an increase in the pre-convulsion time or convulsions will not occur in the guinea pigs who will be pretreated with it, antagonistic effects on the trachea chains and ileum and also anti-inflammatory effect in the rats. Prod. Medical provision in Africa—P. 2Faculty of Agriculture Education, University of Education, Winneba, Ghana. E-mail: aasase@ug.edu.gh (Received … Harvesting of such species should be regulated by the forestry commission of Ghana. The most consumed of thymus is as medicine, food flavoring and herbal tea in Iran. It is claimed to be used by traditional practitioners in Northwestern Nigerian for the management of mental illnesses. E. alba methanol extract showed the highest of total phenolic content (17.88 ±0.93 mg GAE/100mg of extract), of total flavonoids (8.02 ± 0.4 mg QE/100 mg of extract) and of total tannins content (6.33 ± 0.29 mg TAE/100mg of extract). The study seeks to determine the fate of liana communities along fire chronosequence. Because of low socio-economic empowerment, traditional beliefs and cultural barriers, the suffering people resort to use of herbal remedies in search of cure especially for rural women who rarely discuss/disclose diseases affecting secretive body parts. Conclusions . The lack of a regulatory policy and protocol for the integration seemed to have led to the different perception of the integration. An ethnobotanical survey was carried out in Ngai subcounty in Apac District. [5] T. Chou (2006) Pharmacol. Taken together, this study confirms the antimalarial activities of Nefang and has identified extract pairs with possible positive interactions for exploitation towards a rational, evidence-based and phytotherapeutic drug discovery in malaria. Thirty-two plant species belonging to twenty-eight families were identified. Join ResearchGate to find the people and research you need to help your work. Traditionally, rural African communities have relied mainly on the invaluable spiritual and practical skills of traditional medicine practitioners (TMPs) for their healthcare. The study was conducted in eight communities in southern Ghana. of a wide array of diseases including tuberculosis, malaria, and inammatory disorders [, , ]. However, ethnopharmacological characterization of traditional medicines used to treat these diseases is lacking. The sun protection factors (SPFs) of the formulations were determined by an in vitro spectrophotometry method. TheImportanceofMedicalPlantsinGhana 3 2.3. Department of Pharmacognosy, Faculty of Pharmacy & Pharmaceutical Sciences, College of Health Sciences, L. (Lamiaceae) were the most commonly mentio, L. (Verbenaceae) was the most-reported anxiolytic product, with. © 2008-2020 ResearchGate GmbH. The results revealed that butanol and chloroform extracts exhibit the strongest effect followed by ethyl acetate suggesting that a combination of different classes of metabolites is likely to mediate the P. edulis anxiolytic effect in these fractions. Scientific Name . some medicinal plants were found to affect the survival of some plants species. Besides there is need for conducting well designed clinical trials so that the promising compounds could be used as effective anti-inflammatory therapeutic agents in future. Although the majority of medicinal plants, derived from the forests, some species are also obta, The government of Ghana, like those of ma, the center, located at Mampong–Akuapim in t, nal plant use in the country through the inclusion, beyond the boundaries of their respective communities due to the inability to raise adequate capital, to increase production and transport them to other parts of the. Cure of inflammatory diseases is a big challenge. Most of these plant species have reported anxiolytic, antidepressant, anticonvulsant, antipsychotic, sedative, anti-Alzheimer's, cognitive enhancement, motor coordination, and neuroprotective properties, Asthma is a non-communicable disease that affect the respiratory system. Traditionally, information on the diversity and uses of medicinal plants in Ghana is only made known through ethnobotanical studies by some individual researchers. It was believed that only plants collected from the wild were effective. The results are discussed and recommendations made for future research to support the conservation and sustainable harvesting of the species reported to have medicinal properties. Nonetheless, there are concerns about, to address these concerns while enhancing the therapeu-, herbal medicine practice and also integrate T, mainstream healthcare system. Two hundred herbalists agreed to participate but sixty-six specialized in treating mental and neurological disorders were interviewed on their traditional medical practice. Pharmacology, School of Health and Life Sciences, De Montfort University, Leicester LE1 9BH, UK, Midlands Integrative Biosciences Training Partnership, Department of Plant and Environmental Biology. Beyond its CNS eect, extracts from the plant. Objective: than  million people reportedly die each year due to stroke, with over % of these deaths occurring in low- and middle-. Also, methanolic extracts of Bixa orellana and Milicia excelsaprepared in concentrations ranging from 3.125mg/ml to 100mg/ml were assessed for their antimicrobial activity using the agar well diffusion method. More than 250 indigenous trees and plants with healing properties have been scientifically catalogued in Ghana. The preliminary phytochemical screening revealed the presence of saponins, triterpenoids, alkaloids, flavonoids, phlobatanins and anthraquinones. The extract of C. americanum presented the best activity for the cation radical ABTS + reducing activity (67.50 ± 3.88 mmol AAE/g). The IC50 value of Molucidin, ML-2-3 and ML-F52 were 1.27 μM, 3.75 μM and 0.43 μM, respectively. The objective of this study therefore was to determine whether the active ingredient of safflower, Several hundred genera are used in herbal remedies and in traditional or folklore medicines throughout the world. Mental and neurological disorders are a serious public health challenge globally, particularly in developing countries where cultural factors and limited access to standard healthcare have led to a reliance on traditional medicines. In this study, an ethnobotanical description of plant species used in treating mental and neurological disorders in Ghana and an update of their experimentally validated pharmacological relevance are provided. Simulations using harvested and unharvested populations yielded significantly different estimates of maximum sustainable harvest limits, indicating that methods for calculating maximum harvest limits that assume linear responses to harvest may lead to erroneous conclusions. edulis Sims, its sub-fractions and avonoid consti, in relation to its metabolite ngerprint as revealed via LC-MS, the pericarp of Passiora edulis avicarpa Degener: Putati. (multi-drug resistant) strains of P. falciparum were analyzed using the SYBR Green 1-based fluorescence assay [2, 3], and the interactions between various extract pairs analyzed using a fixed-ratio drug combination approach [4]. Given the high proportion of patients using herbal medicine in Ghana, some health facilities have initiated implementation of herbal medicine as a component of their healthcare delivery. Derailed inflammation causes severe damage to the normal tissues resulting in various pathological conditions such as auto-inflammatory disorders, neurodegenerative diseases and cancer. Parasitol., 65, 418-420. –, . Although a large number of anti-inflammatory herbal compounds have been isolated but the mechanism of action of bulk of compounds has not been elucidated comprehensively. The spasmolytic effect of the fruit juice on histamine-induced bronchospasm, isolated ileum and trachea chains of guinea pigs, and the anti-inflammatory effects in rats will be assessed. 2005; Addo-Fordjour et al. Populations concurrently harvested for leaves and ramets had higher maximum sustainable levels of ramet harvest than those harvested for ramets only. This study will provide a basis for future studies to develop safflower extracts using advanced composition technology and contribute to the development of the herbal cosmetics industry. 1812 adults enrolled for care in the neurology out-patient service between 2011 and 2013. The antiproliferative activity was performed by the MTT assay on LNCaP and PC-3 cell lines of prostate cancer and SF-767 and SF-763 cell lines of glioblastoma. With the current increase in the, The objectives of these studies were to ascertain the efficacy and safety of medicinal plants used by herbalists to manage non-communicable diseases, such as diabetes, diarrhea, hypertension, asthm, Essential oils are natural complex of volatile and odorous molecules, synthesized by aromatic plants. See color insert.) sent, Ethical Approval, and Data Collection. –, . 2008). Plants and plant-derived food products have been used for medicinal purposes since the ancient. chotic experiences in kenyan children and adolescents, neurological impairments associated with neglec. In this study, we identified three novel tetracyclic iridoids, Molucidin, ML-2-3 and ML-F52 from the CHCl3 fraction of M. lucida leaves, possessing activity against the GUTat 3.1 strain of T. b. brucei. You can browse alphabetically by common names, to find information on a popular herb like ginger, or find it listed by its botanical name, Zingiber officinale. The bark from the black cherry tree was often made into a tea or syrup and used to expel worms, heal ulcers and treat burns. in vivo antiplasmodial efficacy. Of the 17 families studied Leguminosae and Anacardiaceae predominated in terms of number of species used to treat malaria. Native to western Africa, the cola plant is related to the cacao, which is used to make chocolate. Antioxidant. is would enable the industrial-, strengthening academia-industry collaborative research and, better provision of research funding and infrastructure [, , e identied natural products used in Ghanaian commu-, the management of mental and neurological disorders. Valuation of African Traditional Medicine: Pharmacological and Toxicological evaluation of medicinal plant used in the management of non-communicable diseases. The medicinal plants were categorised into four growth forms: trees (63.5%), climbers (15.4 %), herbs (11.5%) and shrubs (9.6%). with the others having anxiolytic (.%), sedative (.%), however, has been previously reported to have antipsycho, F : Plant families comm, administered as monopreparations (prepared using a single, stem barks, whole plant of shrubs, etc. Conclusions: acid stearoyl glucoside isolated from lantana camara. essential oil of Ocimum gratissimum L. (Labiatae) in mice, ties of aqu eous leaves extra ct of Ocimum Grati ssimum (Labiate). The aim of the present study was to evaluate the antioxidant capacity, the Lipoxygenase and Acetylcholinesterase inhibition potentials and the phenolic content of these three species. Multivariate data analysis (PCA) was further applied to identify metabolite markers for active fractions and reveal the enrichment of C-glycoside type flavonoids in chloroform/ethyl acetate fractions versus the trypanosomal infections in both humans and animals. Sort by Category . Plants. The species used for the isolation of active ingredients may be indigenous species growing wild or cultivated, or hybrids or other cultivated varieties that have been bred for a particular characteristic. The objective of this study was to investigate the effects of saffron as a natural sunscreen and moisturizer. These were used to treat a variety of diseases. Journal of Complementary and Alternative Medical Research. The study documented 67 medicinal plants distributed among 27 families and 51 genera used to treat fungal and bacterial infections in and around Queen Elizabeth Biosphere Reserve in western Uganda. , no. In Morocco, diabetes mellitus is a major public health problem with over than 1.5 million cases in 2014. C. americanum showed the best value of 0.96 ± 0.11 mg QE/100mg of extract for total flavonols content. Successful conservation of nontimber products and their rainforest habitats requires the identification of optimal harvest regimes, the accurate estimation of maximum harvest limits, and the implementation of those limits by local harvesters. Economic Research on the Global Environment, University Colle. Information on the medicinal plants was obtained from semi-structured questionnaires, interviews and field excursions involving herbalists and taxonomists. Mostof the herbal medicines were Does Saffron Have Antisolar and Moisturizing Effects? enriched extract from Rauwola vomitoria, Disease and Mortality in Sub-Saharan Africa, edition, , http://www.ncbi.nlm.nih.gov/books/NBK, and antiinammatory activities of the ethyl acetate fraction of. The most commonly harvested plant parts were leaves (40.3 %). Ethnopharmacological Relevance . indica fruit extract on cognitive decits in mice, pressant and anxiolytic properties of the methanolic extract of, Momordica charantia Linn (Cucurbitaceae) and its mechanism, of ocimum gratissimum L. (Lamiaceae) essential oil and its. The study was conducted at the neurology clinic of the Komfo Anokye Teaching Hospital in Kumasi, Ghana. Journal of Medicinal Plants Research Full Length Research Paper Exploitation and use of medicinal plants, Northern Region, Ghana Imoro Abukari Ziblim*, Khan Aikins Timothy and Eledi James Deo-Anyi University for Development Studies, Department of Range and Wildlife Management, Nyankpala Campus. Medicinal Plants, a critical factor in wild harvesting is the availability of cheap labour to undertake the very labour intensive work of gathering. The most commonly cited medicinal plant species were Azadirachta indica, Alstonia boonei, Morinda lucidaand Nauclea latifolia, mostly used to treat human conditions such as malaria, jaundice, rheumatism, andcough. A number of medicinal plants have been used by traditional healers in the management of many ailments for many years, ... Habitat of this plant is wide areas of Iran such as the high lands of western, northwestern, central and south areas (Rechinger, 1982). None of the herbalists had garden(s) where medicinal plants were cultivated. In a country where oral transmission of knowledge, sition and preservation (Abel and Busia 2005), Ghana stands a high risk of losing vital information, the herbalists a repository of information on medicinal plants, but the younger generation also does, in the profession. C. citratus has submitted the best antiproliferative activity on both cell lines LNCaP (IC 50 = 6.36 μg/ml) and PC-3 (IC 50 = 32.1μg/ml) of prostate cancer than those SF-767 (IC 50 = 45.13μg/ml) and SF-763 (IC 50 = 172.05μg/ml) of glioblastoma. Information about the medicinal plants and traditional healing was gathered using questionnaires, semi-structured interviews, informal discussion and field excursion which yielded lists of local plant names, names of diseases treated, mode of administration and parts used. The reasons for the rise in interest in herbal medicine on the continent are explained briefly and the need for stricter regulatory controls of the herbal industry, advocated. C. citratus has presented the best ability to scavenge DPPH . Trypanosoma brucei parasites are a group of kinetoplastid protozoa which devastate health and economic well-being of millions of people in Africa Thus, in contrast to Western medicine, which is based on the biomedical model, traditional African medicine takes a holistic approach: disease, good health, success or failure, are believed to be the products of the actions of individuals and ancestral spirits according to the balance or imbalance between the individual and the social environment. In addition, the CNS/PNS diseas, in Africa is exacerbated by the numerous but understudied, neurological impairments associated with common tropical, diseases such as the neglected tropical diseas, takes pride in the longstanding cultural use of traditional, and alternative medicines (TAMs), as exhibited by the s, published works on the ethnobotanical use of TAMs in, the country [–]. Top 65 Most Commonly Used Herbs; All-Heal, Prunella vulgaris L. Aloe Vera … (Fabaceae), and Persea Americana Mill (Lauraceae) being the most studied anticonvulsants. Because in many cases income from such sources represents the only form of paid employment for inhabitants of remote rural areas, there is a ready availability of workers. Thus, the planting of diverse population in the equal environmental conditions will reduce the environmental impacts on incidence of vegetative traits, also better reveals the diversity of genetical differences between populations. The 4% saffron lotion showed an SPF value equivalent to the 8% homosalate lotion reference by an in vitro method. Results: All oils were presented antioxidant and anti-inflammatory activity. Despite, the importance of TK on plants, it is widely disappearing due to globalization that promotes intensive agriculture, changes in . This article contains data on in vitro antimycobacterial activity and cytotoxicity of hydroethanolic crude extracts from five selected medicinal plant species traditionally used to treat tuberculosis in Ghanaian ethnomedicine, see “Medicinal plants used to treat TB in Ghana” [1]. Recently, safflower has attracted interest because of its ability to control fine wrinkle formation on the neck. The aim of the present study was to document herbal medicines used by traditional healers to treat and manage human diseases and ailments by some communities living in Ghana. Maximum harvest rates of ramets from secondary forest populations were much higher than from primary-forest populations. According to the economic importance of thyme, identify of morphological characteristics and essential oil content is important in different populations. The essential oils were extracted by hydrodistillation using a Clevenger-type apparatus adapted and analyzed by GC/MS and GC/FID. The herbalists confirmed a decrease in the richness and abundance of some of plant species including threatened ones. Acknowledgement: Thanks go to Institut Pasteur, Korea for the internship/training course in Biosafety and Drug Discovery. It is essential to study these plants in a bid to evaluate their therapeutic properties, adding credence to their applications in folklore. We also tested the accuracy of estimating maximum harvest limits using matrix-model projections of unharvested populations. Based on the qualitative traits, populations were classified in five main groups. Cluster analysis of quantitative traits divided three main groups in thymus populations and Azarbayejangharbi populations were separated partially. According to the United Nations Food and Agriculture Organization, the cola plant is one of the foremost edibles grown in Ghana. Consequently, scanty literature exists on the medicinal uses of many plants in the forests of Ghana. Whilst biomedical health workers perceived the system to be parallel than integrated, health personnel providing herbal medicine perceived the system as integrated. Overall, .% of the, 3.4. The commonest primary neurological disorders seen were strokes, epilepsy and seizure disorders, and movement disorders at frequencies of 57.1%, 19.8%, and 8.2% respectively. Previous studies have demonstrated its in vitro antiplasmodial activity, synergistic interactions between its constituents, antioxidant properties and, Ethnopharmacological evidence of the folk use of Nefang, a polyherbal product composed of Mangifera indica (bark and leaf), Psidium guajava, Carica papaya, Cymbopogon citratus, Citrus sinensis, Ocimum gratissimum (leaves), for the treatment of malaria has been reported previously [1]. The S. aureus isolates showed a dose-dependent sensitivity to the test extracts with sensitivity reducing at lower concentrations. Keywords: Traditional medicine, herbal remedies, conservation, ghana Address for Correspondence: Alex Asase, Department of Botany, University of Ghana, P. O. To profile the frequency of neurologic disorders and basic demographic data in an adult neurology out-patient service commissioned in 2011 in Kumasi, Ghana. Such compounds act at multiple targets in the inflammatory response pathways and regulate multitude of chemical mediators, enzymes, genes or cellular functions to alleviate inflammation. addition, realizing the huge potential Of herbal medicines, twenty pharmaceutical companies applied for manufacturing herbal medicine in Bangladesh. In such a case, plan, benets are observed when used as combina, traditional healers should be explored further to identify their, discovery and development research should be conducted, on the reported plant products to identify lead, clinical and clinical studies. Paullinia pinnata : Roots are used … a section of a map of africa showing Ghana. Agents Chemotherap., 2002, 2518-2524. Bangladesh have therapeutic values (Yusuf et al.. 1994 and Ghana, 1998). The extract of E. alba showed the best inhibitory activity of Acetylcholinesterase, enzyme involved in Alzheimer's disease with a inhibition percentage of 23.44 ± 0.96% and also the best value for the inhibition of Lipoxygenase (42.76 ± 2.45 %) at a concentration of 100µg/mL. To further pinpoint bioactive agents in fractions, ultra-performance liquid chromatography (UPLC) coupled to high resolution qTOF-MS was used for secondary metabolite profiling. DNA barcoding is the best identification tool for medicinal plants species which when accepted for use will completely eliminate misidentification and help in the proper A total of 52 plant species belonging to 47 genera and 22 families were identified by the traditional herbalists as medicinal plants. Most of the identified plants have been scientifically confirmed to possess neuro- and psychopharmacological properties and may serve as templates for drug development. Transmission of knowledge to trainees was mainly informal. C. citratus and citral also lead repression of Rb, activation of p21 and P27 of cycle. It did not significantly alter the time taken to complete task and the number of foot slips in the beam walking assay. There were no significant differences of skin moisture contents after application of the saffron lotions and the control base lotion without saffron. We examined the effects of three types of variation on maximum harvest rates: variation between forest types, between harvest regimes, and over time. rather over 60% of the population in Ghana largely depend on medicinal plants for their health needs. Species, Medicinal Uses, and Experiment, Asteraceae, and Meliaceae were the most mentioned plant, families, with Apocynaceae having the hig, mentions and Asteraceae having the highest number of plant, previously reported to have neuropharmacological, Half of the identied TAMs had analgesic (. , no. The results showed that the most content of essential oil and the highest mean of the most morphological traits were belonged to Azarbayejangharbi-I, IV and Tehran populations. © 2008-2020 ResearchGate GmbH. 40K present in some selected medicinal plants commonly used in Ghana from the Centre for Scientific Research into Plant Medicine (CSRPM) at Mampong-Akuapem in the Eastern Region and to assess the radiological risk associated with the use of these medicinal plants. is low, managed by community pharmacists and primary, indicating that several individuals with headache or migraine, were oen used by the TMPs, suggesting a potentially hig, prevalence of anxiety disorders and epilepsy and seizure. Of Bixa orellana Linn for the management of mental illnesses food products have been scientifically confirmed to neuro-! Americanum presented the best value medicinal plants in ghana pdf Molucidin, ML-2-3 and ML-F52 were 1.27 μM, 3.75 μM and 0.43,! 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